Francis K. Yoshimoto, Ph.D.
Ph.D. in Biochemistry; University of Texas Southwestern Medical Center at Dallas
B.S. in Chemistry; University of California, Berkeley
B.A. in Linguistics; University of California, Berkeley
Research in this laboratory combines interdisciplinary approaches in chemistry and biology to solve problems that will benefit human health. In this regard, studies are related to exploring the mechanisms of cytochrome P450 enzymes, a super family of enzymes found in all kingdoms of life. Humans have 57 cytochrome P450 enzymes that are directly related to a variety of human health conditions such as neurodegenerative diseases, cancer, and cardiovascular health. Furthermore, plants are a rich resource of cytochrome P450 enzymes, which are responsible in the production of medicinal compounds (i.e. natural products). These natural products possess many activities that benefit human health such as anti-cancer, anti-malarial, and anti-bacterial properties.
Ultimately, our research efforts focus on discovering fundamental aspects of biochemical processes that address global health problems.